SCHEMBL21392691

SCHEMBL21392691

Cc1cc(C(C)(C)c2cc(C)c(C(C)(C)c3cc(O)c(O)c(O)c3)c(C)c2)cc(C)c1C(C)(C)c1cc(O)c(O)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.48
ALOX15 P16050 4/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
ALOX12 P18054 2/20 0.45
ALDH1A1 P00352 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 2/20 0.45
TSHR P16473 2/20 0.45
CASP1 P29466 1/20 0.45
RECQL P46063 1/20 0.45
HIF1A Q16665 1/20 0.45
SELL P14151 1/20 0.42
SELP P16109 1/20 0.42
SELE P16581 1/20 0.42
GPR35 Q9HC97 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
CHEK1 O14757 1/20 0.38
DAPK3 O43293 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24748740 0.89 ESR1 (0.58) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL8407833 0.86 ALOX15 (0.56) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL23221097 0.82 ESR1 (0.64) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL5676183 0.79 ESR1 (0.56) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL19765500 0.77 ESR1 (0.56) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL69586 0.76 ALDH1A1 (0.56) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL25567739 0.75 ESR1 (0.41) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL4058746 0.74 ESR1 (0.61) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL29472991 0.74 ALDH1A1 (0.54) ESR1ALOX15HPGDHSD17B10ALOX12
SCHEMBL2618674 0.74 ALDH1A1 (0.54) ESR1ALOX15HPGDHSD17B10ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218123-A1 BIFUNCTIONAL SIZING AGENT FOR IMPROVED ADHESION TO SUBSTRATES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-07-04 US disclosed
US-20240216874-A1 SELECTIVELY PERMEABLE MEMBRANE OBTAINED BY CARBONIZATION SULFONATED POLY(PHENYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2024-07-04 US disclosed
US-20210388206-A1 POLYMER-CERAMIC COMPOSITE ARTICLES WITH LOW DISSIPATION FACTOR AND HIGH DIELECTRIC CONSTANT, AND CORE-SHELL PARTICLE POWDERS AND PROCESSES FOR MAKING SUCH ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
WO-2021198987-A1 METHOD OF MAKING A HIGH FILLED FIBER-MESH REINFORCED CERAMIC-THERMOPLASTIC POLYMER COMPOSITES WITH OUTSTANDING MECHANICAL PERFORMANCE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 WO disclosed
EP-3889208-A1 METHOD OF MAKING A HIGH FILLED FIBER-MESH REINFORCED CERAMIC-THERMOPLASTIC POLYMER COMPOSITES WITH OUTSTANDING MECHANICAL PERFORMANCE SHPP Global Technologies B.V. (NL) 2021-10-06 EP disclosed
WO-2021070138-A1 POLYMER-CERAMIC COMPOSITE HOUSINGS AND HOUSING COMPONENTS FOR PORTABLE ELECTRONIC DEVICES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-04-15 WO disclosed
US-10767010-B2 Purified poly(phenylene ether), and poly(phenylene ether) composition and article SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-08 US disclosed
US-20190292316-A1 PURIFIED POLY(PHENYLENE ETHER), AND POLY(PHENYLENE ETHER) COMPOSITION AND ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-09-26 US disclosed