SCHEMBL4058746

SCHEMBL4058746

CC(C)(c1cccc(C(C)(C)c2cc(O)c(O)c(O)c2)c1)c1cc(O)c(O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.61
ESR2 Q92731 4/20 0.61
CNR1 P21554 4/20 0.49
CNR2 P34972 4/20 0.49
ALOX15 P16050 5/20 0.48
ALOX12 P18054 2/20 0.48
ALDH1A1 P00352 4/20 0.45
HPGD P15428 4/20 0.45
HSD17B10 Q99714 4/20 0.45
CYP3A4 P08684 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
RECQL P46063 2/20 0.45
TSHR P16473 2/20 0.45
CASP1 P29466 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
KLF10 Q13118 1/20 0.42
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8407833 0.86 ALOX15 (0.56) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL5676183 0.84 ESR1 (0.56) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL1346737 0.83 ESR1 (0.67) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL237756 0.83 ESR1 (0.61) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL18855335 0.81 CHEK1 (0.60) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL582052 0.79 TSHR (0.76) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL4460477 0.78 ESR1 (0.60) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL10492961 0.77 ESR1 (0.72) ESR1ESR2CNR1CNR2ALDH1A1
SCHEMBL29696059 0.77 ESR1 (0.83) ESR1ESR2CNR1CNR2ALOX15
SCHEMBL697802 0.77 ESR1 (0.83) ESR1ESR2CNR1CNR2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR1 392/4885ESR2 895/4885CNR1 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.