SCHEMBL24748740

SCHEMBL24748740

Cc1cc(C(C)(C)c2cc(C)c(C(C)(C)c3cc(O)c(O)c(O)c3)c(C)c2)cc(C)c1C(C)(C)c1ccc(O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.58
ALOX15 P16050 3/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALOX12 P18054 2/20 0.49
KLF10 Q13118 1/20 0.43
RORC P51449 1/20 0.40
ESR2 Q92731 5/20 0.39
AR P10275 3/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
CASP1 P29466 1/20 0.37
RECQL P46063 1/20 0.37
HIF1A Q16665 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
SLC6A2 P23975 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23221097 0.95 ESR1 (0.64) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL21392691 0.89 ESR1 (0.48) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL1501111 0.81 ALDH1A1 (0.73) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL5676183 0.79 ESR1 (0.56) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL5674836 0.79 ALDH1A1 (0.70) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL8407833 0.77 ALOX15 (0.56) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL726372 0.76 ESR1 (0.83) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL30607257 0.76 ESR1 (0.83) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL3913903 0.75 ESR1 (0.91) ESR1ALOX15HPGDHSD17B10ALDH1A1
SCHEMBL29350788 0.75 ESR1 (1.00) ESR1ALOX15HPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805300-B1 POLYMER-CERAMIC COMPOSITE HOUSINGS AND HOUSING COMPONENTS FOR PORTABLE ELECTRONIC DEVICES SHPP GLOBAL TECH BV (NL) 2022-12-21 EP disclosed