Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | MITF | O75030 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806908 | 0.81 | RNF4 (0.86) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3382618 | 0.78 | RNF4 (1.00) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21392894 | 0.76 | L3MBTL1 (0.47) | RNF4TAAR1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL21392968 | 0.75 | RNF4 (0.76) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23748676 | 0.74 | RNF4 (0.73) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4708278 | 0.74 | TAAR1 (0.67) | TAAR1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23748680 | 0.73 | RNF4 (0.71) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23748677 | 0.72 | RNF4 (0.75) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31536277 | 0.72 | RNF4 (0.75) | RNF4ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19662081 | 0.71 | TAAR1 (0.53) | TAAR1ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | RNF4 1274/4885TAAR1 4233/4885ALDH1A1 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.