Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNF4 | P78317 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | FNTA | P49354 | 5/20 | 0.59 |
| ▸ | FNTB | P49356 | 5/20 | 0.59 |
| ▸ | MITF | O75030 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806908 | 0.93 | RNF4 (0.86) | RNF4ALDH1A1L3MBTL1MITFHTT | |
| SCHEMBL16922181 | 0.89 | NPC1 (0.66) | RNF4ALDH1A1MITFHTTPOLB | |
| SCHEMBL1503954 | 0.89 | NPC1 (0.66) | RNF4ALDH1A1MITFHTTPOLB | |
| SCHEMBL3382618 | 0.86 | RNF4 (1.00) | RNF4ALDH1A1MITFHTTPOLB | |
| SCHEMBL23748676 | 0.85 | RNF4 (0.73) | RNF4ALDH1A1L3MBTL1FNTAFNTB | |
| SCHEMBL4747363 | 0.85 | ALDH1A1 (0.64) | RNF4ALDH1A1L3MBTL1FNTAFNTB | |
| SCHEMBL2171671 | 0.85 | L3MBTL1 (0.68) | RNF4ALDH1A1L3MBTL1FNTAFNTB | |
| SCHEMBL31703396 | 0.85 | RNF4 (0.73) | RNF4ALDH1A1L3MBTL1FNTAFNTB | |
| SCHEMBL22069619 | 0.84 | PNLIP (0.64) | HTTMEN1KMT2ANPSR1PNLIP | |
| SCHEMBL31536382 | 0.84 | PNLIP (0.64) | HTTMEN1KMT2ANPSR1PNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217513-A1 | ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2025-10-16 | — | — | WO | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | RNF4 1274/4885ALDH1A1 4188/4885L3MBTL1 625/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | RNF4 2/4885ALDH1A1 2969/4885L3MBTL1 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.