Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544515 | 0.90 | RXFP1 (0.62) | ALDH1A1L3MBTL1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL203013 | 0.85 | HPGD (0.63) | ALDH1A1RXFP1PNLIPKMT2ASMN1; SMN2 | |
| SCHEMBL23966424 | 0.85 | RXFP1 (0.54) | ALDH1A1L3MBTL1RXFP1PNLIPKMT2A | |
| SCHEMBL3194415 | 0.85 | RXFP1 (0.54) | ALDH1A1RXFP1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11656245 | 0.83 | KMT2A (0.69) | ALDH1A1L3MBTL1PNLIPKMT2ASMN1; SMN2 | |
| SCHEMBL9397597 | 0.81 | MEN1 (0.52) | ALDH1A1L3MBTL1PNLIPKMT2ASMN1; SMN2 | |
| SCHEMBL3199696 | 0.81 | RXFP1 (0.50) | ALDH1A1RXFP1PNLIPKMT2ASMN1; SMN2 | |
| SCHEMBL7603741 | 0.81 | PKM (0.50) | ALDH1A1RXFP1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL439393 | 0.80 | RXFP1 (0.74) | ALDH1A1L3MBTL1RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL3187581 | 0.80 | RXFP1 (0.49) | ALDH1A1RXFP1PNLIPKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | ALDH1A1 4188/4885L3MBTL1 625/4885RXFP1 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.