Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 9/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394421 | 0.91 | MRGPRX1 (0.46) | MRGPRX1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21384571 | 0.85 | MRGPRX1 (0.60) | MRGPRX1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21384565 | 0.83 | CNR2 (0.36) | MRGPRX1SCN9ASCN5A | |
| SCHEMBL21384613 | 0.78 | MRGPRX1 (0.61) | MRGPRX1TP53MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL21384586 | 0.75 | CNR2 (0.37) | MRGPRX1 | |
| SCHEMBL21384561 | 0.73 | ACLY (0.48) | MRGPRX1TP53SCN9ASCN5AKDM4E | |
| SCHEMBL21384579 | 0.71 | MRGPRX1 (0.41) | MRGPRX1MAPTSCN9ASCN5A | |
| SCHEMBL21384576 | 0.69 | MRGPRX1 (0.63) | MRGPRX1KDM4ETSPOTMPRSS4HRH1 | |
| SCHEMBL21394560 | 0.69 | MRGPRX1 (0.51) | MRGPRX1TP53MAPTTSPOTMPRSS4 | |
| SCHEMBL21381353 | 0.69 | MRGPRX1 (0.62) | MRGPRX1MAPTRAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |