Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394531 | 0.88 | MEN1 (0.58) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL21394621 | 0.87 | RXFP1 (0.50) | RXFP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21394794 | 0.82 | DGAT1 (0.54) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL29358244 | 0.79 | ALDH1A1 (0.48) | RXFP1MEN1KMT2ANPC1ABL1 | |
| SCHEMBL21394510 | 0.79 | ALDH1A1 (0.48) | RXFP1MEN1KMT2ANPC1ABL1 | |
| SCHEMBL21394825 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29356860 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3669882 | 0.75 | DGAT1 (0.77) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL30397132 | 0.75 | ALDH1A1 (0.53) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL30397171 | 0.74 | ALDH1A1 (0.57) | DGAT1RXFP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |