Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394536 | 0.88 | DGAT1 (0.56) | MEN1KMT2ADGAT1NPC1RXFP1 | |
| SCHEMBL21394794 | 0.88 | DGAT1 (0.54) | MEN1KMT2ADGAT1NPC1RXFP1 | |
| SCHEMBL21394621 | 0.85 | RXFP1 (0.50) | MEN1KMT2ANPC1RXFP1RAB9A | |
| SCHEMBL21394526 | 0.83 | SCD (0.60) | MEN1KMT2ANPC1RAB9AABL1 | |
| SCHEMBL21395167 | 0.82 | LMNA (0.60) | MEN1KMT2ADGAT1NPC1RXFP1 | |
| SCHEMBL29353926 | 0.79 | CREBBP (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL21394413 | 0.79 | CREBBP (0.55) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL29357564 | 0.79 | CREBBP (0.45) | MEN1KMT2ANPC1RAB9AABL1 | |
| SCHEMBL21394445 | 0.79 | CREBBP (0.45) | MEN1KMT2ANPC1RAB9AABL1 | |
| SCHEMBL21394601 | 0.77 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |