Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394536 | 0.87 | DGAT1 (0.56) | RXFP1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL21394794 | 0.86 | DGAT1 (0.54) | RXFP1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL21394531 | 0.85 | MEN1 (0.58) | RXFP1KMT2AMEN1POLBGAA | |
| SCHEMBL22479682 | 0.84 | LMNA (0.59) | RXFP1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL29357123 | 0.79 | MAOB (0.42) | KMT2AMEN1CYP3A4NPC1RAB9A | |
| SCHEMBL21394761 | 0.79 | MAOB (0.42) | KMT2AMEN1CYP3A4NPC1RAB9A | |
| SCHEMBL3467629 | 0.72 | L3MBTL1 (0.71) | RXFP1L3MBTL1KMT2AMEN1POLB | |
| SCHEMBL21395161 | 0.70 | LMNA (0.59) | L3MBTL1KMT2AMEN1POLBNPC1 | |
| SCHEMBL22479582 | 0.70 | MEN1 (0.46) | KMT2AMEN1CYP3A4NPC1RAB9A | |
| SCHEMBL14109415 | 0.70 | GPR52 (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |