Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394531 | 0.88 | MEN1 (0.58) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL21394621 | 0.86 | RXFP1 (0.50) | RXFP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21394536 | 0.82 | DGAT1 (0.56) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL15655625 | 0.79 | NPC1 (0.82) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL29353782 | 0.76 | KDM4E (0.51) | RXFP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394550 | 0.76 | KDM4E (0.51) | RXFP1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24846070 | 0.73 | TSHR (0.61) | MEN1KMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3673362 | 0.73 | DGAT1 (0.76) | DGAT1RXFP1MEN1KMT2ANPC1 | |
| SCHEMBL30397125 | 0.71 | L3MBTL1 (0.57) | DGAT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3728387 | 0.71 | DGAT1 (0.52) | DGAT1RXFP1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |