Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394703 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2F10ALDH1A1 | |
| SCHEMBL21394699 | 0.86 | FFAR2 (0.42) | NPC1RAB9ASMN1; SMN2PPARGTDP1 | |
| SCHEMBL21394653 | 0.86 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2PPARGTDP1 | |
| SCHEMBL21394645 | 0.85 | DEGS1 (0.42) | F10ALDH1A1S1PR1S1PR3KDM4E | |
| SCHEMBL21395072 | 0.84 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2PPARGTDP1 | |
| SCHEMBL21395146 | 0.81 | KCNQ3 (0.44) | NPC1RAB9ASMN1; SMN2PPARGTDP1 | |
| SCHEMBL21394717 | 0.81 | CACNA1H (0.39) | NPC1RAB9ASMN1; SMN2PPARGTDP1 | |
| SCHEMBL21394702 | 0.79 | MAOB (0.44) | NPC1RAB9ASMN1; SMN2F10ALDH1A1 | |
| SCHEMBL21395182 | 0.78 | GSK3B (0.44) | NPC1RAB9ASMN1; SMN2F10ALDH1A1 | |
| SCHEMBL21395025 | 0.77 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2PPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |