Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394717 | 0.88 | CACNA1H (0.39) | FFAR2CACNA1HCACNA1GCACNA1INPC1 | |
| SCHEMBL21394929 | 0.86 | NPC1 (0.39) | FFAR2CACNA1HCACNA1GCACNA1INPC1 | |
| SCHEMBL21394700 | 0.86 | ALDH1A1 (0.46) | FFAR2NPC1RAB9APYGLDEGS1 | |
| SCHEMBL21394702 | 0.83 | MAOB (0.44) | NPC1RAB9ASMN1; SMN2DEGS1F10 | |
| SCHEMBL21395182 | 0.83 | GSK3B (0.44) | NPC1RAB9ASMN1; SMN2DEGS1F10 | |
| SCHEMBL21394653 | 0.82 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2DEGS1TDP1 | |
| SCHEMBL21395025 | 0.82 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TDP1PPARG | |
| SCHEMBL21394645 | 0.82 | DEGS1 (0.42) | DEGS1F10ALDH1A1 | |
| SCHEMBL21394713 | 0.81 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TDP1PPARG | |
| SCHEMBL21395072 | 0.80 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TDP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |