SCHEMBL21396793

SCHEMBL21396793

N#Cc1ccc(N2c3ccccc3Oc3ccccc32)c(-c2cccnc2N2c3ccccc3Oc3ccccc32)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 1/20 0.33
BRD4 O60885 2/20 0.33
SLC40A1 Q9NP59 1/20 0.33
AVPR1A P37288 1/20 0.32
DDB1 Q16531 1/20 0.32
CRBN Q96SW2 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
CASP3 P42574 1/20 0.32
CLK4 Q9HAZ1 1/20 0.31
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21396717 0.90 EGLN1 (0.31) USP30BRD4
SCHEMBL18361011 0.86 CASP3 (0.40) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL21397202 0.84 PGR (0.38) USP30BRD4SLC40A1DDB1CRBN
SCHEMBL21396739 0.84 PDK2 (0.36) USP30BRD4SLC40A1DDB1CRBN
SCHEMBL21397045 0.83 KMT2A (0.41) USP30BRD4SLC40A1GABRA1GABRG2
SCHEMBL21691991 0.82 P2RX4 (0.37)
SCHEMBL21396640 0.81 BRD4 (0.36) USP30BRD4SLC40A1GABRA1GABRG2
SCHEMBL21396792 0.81 CYP11B2 (0.37) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL18361183 0.79 CASP3 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL18360980 0.78 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296247-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC25A21, SLCO4C1, SLC18A1 USP30 3777/4885BRD4 344/4885SLC40A1 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.