SCHEMBL21399178

SCHEMBL21399178

O=C(O[Si](c1ccccc1)(c1ccccc1)c1ccccc1)C(F)=C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.36
ACHE P22303 2/20 0.32
CES2 O00748 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
NR1H2 P55055 1/20 0.30
NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4274822 0.78 CES1 (0.43) CES1ACHEHDAC6HDAC1HDAC2
SCHEMBL21399435 0.78 CES1 (0.37) CES1ACHECES2HDAC6HDAC1
SCHEMBL28422623 0.78 LMNA (0.37) CES1CES2
SCHEMBL21382642 0.75 ALDH1A1 (0.32) NR1H2NR1H3
SCHEMBL21399180 0.72
SCHEMBL1053099 0.69 CES1 (0.42) CES1ACHEHDAC6HDAC1HDAC2
SCHEMBL2184872 0.69 ELANE (0.46) CES1CES2
SCHEMBL4281419 0.69 CES1 (0.42) CES1ACHEHDAC6HDAC1HDAC2
SCHEMBL704476 0.69 CES2 (0.41) CES1CES2
SCHEMBL21399183 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019181240-A1 ELECTROLYTIC SOLUTION, ELECTROCHEMICAL DEVICE, LITHIUM ION SECONDARY BATTERY, AND MODULE ダイキン工業株式会社 2019-09-26 WO disclosed