Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904098 | 0.89 | PTGS2 (0.37) | NOTUMSPRALDH1A1MAPK1CNR1 | |
| SCHEMBL9895440 | 0.83 | IDO1 (0.41) | ALDH1A1KCNN4HPGDSMN1; SMN2 | |
| SCHEMBL9895332 | 0.81 | SPR (0.38) | NOTUMSPRALDH1A1RORCLDHA | |
| SCHEMBL9895495 | 0.76 | SPR (0.37) | HSP90AA1SPRKCNN4 | |
| SCHEMBL9896773 | 0.73 | GABRA5 (0.37) | SPR | |
| SCHEMBL21402163 | 0.73 | PTGS2 (0.40) | NOTUMALDH1A1 | |
| SCHEMBL21416227 | 0.71 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9895387 | 0.70 | CNR2 (0.40) | SPRKCNN4CNR1 | |
| SCHEMBL9895210 | 0.70 | PTGS2 (0.46) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9894508 | 0.70 | CYP2C9 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649064-B1 | NOVEL TRIAZOLE COMPOUNDS III | HOFFMANN LA ROCHE (CH) | 2019-10-02 | — | — | EP | claimed |