Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819844 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL12952524 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL13760019 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL2067591 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL2068549 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL607797 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL2068561 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP2C19L3MBTL1TDP1ATM | |
| SCHEMBL3633522 | 0.76 | SLC1A3 (0.43) | ALDH1A1CYP2C19L3MBTL1ATMKMT2A | |
| SCHEMBL3630665 | 0.76 | SLC1A3 (0.43) | ALDH1A1CYP2C19L3MBTL1ATMKMT2A | |
| SCHEMBL3630043 | 0.76 | SLC1A3 (0.43) | ALDH1A1CYP2C19L3MBTL1ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258477-B1 | CATALYST AND MICHAEL ADDITION REACTION PROCESS | JAPAN SCIENCE & TECH AGENCY (JP) | 2015-03-25 | — | — | EP | disclosed |
| US-8987495-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-8563765-B2 | Diamino acid derivative starting material, manufacturing method thereof, and diamino acid derivative manufacturing method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8222177-B2 | Catalyst and reaction process | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8222177-B2 | Catalyst and reaction process | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-03 | — | — | US | disclosed |
| WO-2009096409-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-06 | — | — | WO | disclosed |
| WO-2009096409-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012016-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | ALDH1A1 131/4885CYP2C19 595/4885L3MBTL1 4200/4885 |
| US-20110071310-A1 | DIAMINO ACID DERIVATIVE STARTING MATERIAL, MANUFACTURING METHOD THEREOF, AND DIAMINO ACID DERIVATIVE MANUFACTURING METHOD | DAO, DDC, DCTD | ALDH1A1 131/4885CYP2C19 595/4885L3MBTL1 4200/4885 |
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | ME1, MAL2, ME2 | ALDH1A1 1375/4885CYP2C19 148/4885L3MBTL1 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.