Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 5/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CTRC | Q99895 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4618146 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL92057 | 0.88 | ALDH1A1 (0.72) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL29932227 | 0.88 | ALDH1A1 (0.72) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL1161501 | 0.88 | ALDH1A1 (0.72) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL29362512 | 0.88 | ALDH1A1 (0.72) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL1435737 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL3184580 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| Calcium SCHEMBL30248603 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL5786859 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP1A2PHLPP2MPLTHRB | |
| SCHEMBL1435734 | 0.87 | ALDH1A1 (0.71) | ALDH1A1CYP1A2PHLPP2MPLTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593079-B1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-16 | — | — | EP | disclosed |
| EP-2593077-B1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9060949-B2 | Menthyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-06-23 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130129646-A1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2593079-A2 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | Symrise AG (DE) | 2013-05-22 | — | — | EP | disclosed |
| EP-2593077-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | Symrise AG (DE) | 2013-05-22 | — | — | EP | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| WO-2010122178-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010097480-A2 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE GMBH & CO. KG (DE) | 2010-09-02 | — | — | WO | disclosed |
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | HENKEL AG & CO. KGAA (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1880007-A2 | PERSONAL CARE COMPOSITIONS AND METHODS FOR THEIR USE | GENENCOR INTERNATIONAL, INC. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007110415-A2 | USE OF DIACETYL TRIMERS AND COSMETIC OR THERAPEUTIC FORMULATIONS CONTAINING THESE COMPOUNDS | SYMRISE GMBH & CO. KG (DE) | 2007-10-04 | — | — | WO | disclosed |
| WO-2006121610-A2 | PERSONAL CARE COMPOSITIONS AND METHODS FOR THEIR USE | GENENCOR INTERNATIONAL, INC. (US) | 2006-11-16 | — | — | WO | disclosed |
| US-20060159637-A1 | Surface-modified, structurally modified titanium dioxides | EVONIK DEGUSSA GMBH (DE) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | CBR1, CYP2A13, CBR3 | ALDH1A1 484/4885CYP1A2 26/4885PHLPP2 3064/4885 |
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | TYR, POLR1C, CUTA | ALDH1A1 1276/4885CYP1A2 1316/4885PHLPP2 726/4885 |
| US-20080038213-A1 | Uv Filters | ERCC4, ERCC1, ERCC5 | ALDH1A1 334/4885CYP1A2 79/4885PHLPP2 2645/4885 |
| US-20060159637-A1 | Surface-modified, structurally modified titanium dioxides | TDO2, TYR, FTO | ALDH1A1 2638/4885CYP1A2 30/4885PHLPP2 3665/4885 |
| US-20130129646-A1 | MENTHYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | TYR, CRAT, SUCLG1 | ALDH1A1 160/4885CYP1A2 180/4885PHLPP2 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.