Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.34 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.34 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30226472 | 0.77 | HCAR2 (0.77) | HCAR2TBXA2RTBXAS1MAPTPLOD2 | |
| SCHEMBL21806049 | 0.76 | HCAR2 (0.57) | HCAR2PLOD2PLOD3PLOD1CES1 | |
| SCHEMBL15113893 | 0.76 | NFE2L2 (0.57) | MAPTALDH1A1CES1NFE2L2CA12 | |
| SCHEMBL14513576 | 0.74 | TSHR (0.48) | ALDH1A1HSD17B10NFE2L2CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL6386625 | 0.74 | HCAR2 (0.55) | HCAR2TBXA2RTBXAS1MAPTPLOD2 | |
| SCHEMBL25142331 | 0.73 | CA1 (0.45) | MAPTALDH1A1HSD17B10NFE2L2CA12 | |
| SCHEMBL2699146 | 0.73 | PLOD2 (0.46) | MAPTPLOD2ALDH1A1CES1NFE2L2 | |
| SCHEMBL2699148 | 0.73 | PLOD2 (0.46) | MAPTPLOD2ALDH1A1CES1NFE2L2 | |
| SCHEMBL25142176 | 0.71 | NR4A1 (0.54) | ALDH1A1CES1 | |
| SCHEMBL25142179 | 0.71 | MAPT (0.54) | MAPTALDH1A1CES1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| WO-2019185875-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053957-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | HCAR2 1087/4885TBXA2R 4182/4885TBXAS1 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.