Sugi Predict

Sugi Predict / Compounds / SCHEMBL21436614

SCHEMBL21436614

SCHEMBL21436614

O=C1c2ccccc2-c2ccc3c4ccc5c6c(ccc(c7ccc1c2c37)c64)-c1cc(Br)ccc1C5=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCL2 P10415 2/20 0.81
▸ PTPRC P08575 3/20 0.62
▸ S100A4 P26447 2/20 0.50
▸ MCL1 Q07820 1/20 0.47
▸ CYP1A2 P05177 5/20 0.46
▸ HIF1A Q16665 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ MAPK1 P28482 4/20 0.46
▸ MAPT P10636 3/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ PABPC1 P11940 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ DNMT1 P26358 1/20 0.46
▸ CASP1 P29466 1/20 0.46
▸ CASP7 P55210 1/20 0.46
▸ GNG2 P59768 1/20 0.46
▸ GNB1 P62873 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30181077 0.97 BCL2 (0.87) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL12960391 0.97 BCL2 (0.87) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL14952682 0.93 BCL2 (0.86) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL14206501 0.90 BCL2 (1.00) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL79475 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL12031457 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2
Anthraquinone SCHEMBL4307959 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL88058 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL12449237 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2
SCHEMBL29354334 0.86 BCL2 (0.60) BCL2PTPRCS100A4MCL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 — — US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 — — EP disclosed
US-11324688-B2 Bicomponent composition WELLA INTERNATIONAL OPERATIONS SWI (CH) 2022-05-10 — — US disclosed
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2022-02-24 — — US disclosed
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-20 — — US disclosed
WO-2022002983-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-01-06 — — WO disclosed
EP-3890683-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-10-13 — — EP disclosed
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210290518-A1 MULTICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2021-09-23 — — US disclosed
US-20210145726-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2021-05-20 — — US disclosed
EP-3817710-A1 MULTICOMPONENT SILICONE COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3817825-A1 MULTICOMPONENT PUR COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-05-12 — — EP disclosed
EP-3787753-A1 MULTICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-03-10 — — EP disclosed
EP-3773922-A1 BICOMPONENT COMPOSITION HFC Prestige International Holding Switzerland S.a.r.l. (CH) 2021-02-17 — — EP disclosed
WO-2020114647-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-06-11 — — WO disclosed
WO-2020007510-A1 MULTICOMPONENT PUR COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2020007511-A1 MULTICOMPONENT SILICONE COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 — — WO disclosed
WO-2019192916-A1 BICOMPONENT COMPOSITION HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2019-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016017-A1 COLOR COATINGS WITH DOWNSTREAM FEATURES KRT18, ITGA5, FLNA BCL2 2770/4885PTPRC 1799/4885S100A4 579/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK BCL2 1163/4885PTPRC 361/4885S100A4 59/4885
US-20210290519-A1 MULTICOMPONENT SILICONE COMPOSITION CUTA, CD99, PLOD3 BCL2 2641/4885PTPRC 2527/4885S100A4 348/4885
US-20220054392-A1 MULTICOMPONENT IN SITU COLORATION COMPOSITION KRT18, PRKDC, VIM BCL2 3545/4885PTPRC 3307/4885S100A4 410/4885
US-11324688-B2 Bicomponent composition KRT18, EXOSC10, EXOSC9 BCL2 2661/4885PTPRC 1341/4885S100A4 57/4885
US-20210290518-A1 MULTICOMPONENT COMPOSITION KRT18, INCENP, IK BCL2 2941/4885PTPRC 833/4885S100A4 49/4885
US-20210145726-A1 BICOMPONENT COMPOSITION KRT18, EXOSC10, EXOSC9 BCL2 2661/4885PTPRC 1341/4885S100A4 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.