Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033573 | 0.91 | TAAR1 (0.34) | ALDH1A1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL4849033 | 0.88 | ALDH1A1 (0.34) | ALDH1A1TSHRKMT2AMTNR1AMTNR1B | |
| SCHEMBL8718608 | 0.83 | HPGD (0.38) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7534967 | 0.83 | GABRA1 (0.37) | ALDH1A1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL3224942 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TSHRKMT2ATAAR1 | |
| SCHEMBL11848934 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRKMT2AMTNR1AMTNR1B | |
| SCHEMBL6580961 | 0.79 | KMT2A (0.33) | ALDH1A1TSHRKMT2A | |
| SCHEMBL3339281 | 0.79 | MTNR1A (0.33) | ALDH1A1TSHRKMT2AMTNR1AMTNR1B | |
| SCHEMBL15544091 | 0.78 | TAAR1 (0.34) | ALDH1A1MTNR1AMTNR1BTAAR1 | |
| SCHEMBL19064354 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985645-B1 | Low molecular weight siloxanes with one functional group | GELEST INC (US) | 2017-03-15 | — | — | EP | disclosed |
| US-8455599-B2 | Asymmetric low molecular weight siloxanes with one functional group | GELEST TECHNOLOGIES, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2345686-A2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2011-07-20 | — | — | EP | disclosed |
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-7799888-B2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| EP-1428795-B1 | SILSESQUIOXANE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | CHISSO CORP (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7463400-B1 | Electrochromic display device | FUJI XEROX CO., LTD. (JP) | 2008-12-09 | — | — | US | disclosed |
| US-7449539-B2 | Silsesquioxane derivative and production process for the same | CHISSO CORPORATION (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20080269429-A1 | LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | GELEST, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| EP-1985645-A2 | Low molecular weight siloxanes with one functional group | GELEST, INC. (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-0970066-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 2000-01-12 | — | — | EP | disclosed |
| US-5872299-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5872298-A | Method of preparing intermediates for retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0855388-A2 | Method for making intermediates useful in synthesis of retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998029401-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 1998-07-09 | — | — | WO | disclosed |
| US-5648511-A | Method for making intermediates useful in the synthesis of retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5583238-A | Method for making intermediates useful in synthesis of retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1996-12-10 | — | — | US | disclosed |
| EP-0730570-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0641333-B1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995014653-A1 | METHOD FOR MAKING INTERMEDIATES USEFUL IN SYNTHESIS OF RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298591-A1 | ASYMMETRIC LOW MOLECULAR WEIGHT SILOXANES WITH ONE FUNCTIONAL GROUP | ILK, LASP1, PCNA | ALDH1A1 2527/4885TSHR 3911/4885KMT2A 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.