Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033573 | 0.91 | TAAR1 (0.34) | HPGDKDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL7534967 | 0.88 | GABRA1 (0.37) | KDM4EALDH1A1HTR1AMAPTELANE | |
| SCHEMBL2144177 | 0.83 | ALDH1A1 (0.34) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL142479 | 0.79 | ADRA2B (0.44) | HPGDKDM4EALDH1A1GAAADRA2B | |
| SCHEMBL29488434 | 0.79 | ADRA2B (0.44) | HPGDKDM4EALDH1A1GAAADRA2B | |
| SCHEMBL15544091 | 0.78 | TAAR1 (0.34) | HPGDKDM4EALDH1A1GAASLC6A2 | |
| SCHEMBL8714191 | 0.78 | — | — | |
| Benzene SCHEMBL11786397 | 0.77 | KDM4E (0.44) | HPGDKDM4EALDH1A1GAAADRA2B | |
| SCHEMBL9839840 | 0.77 | ADRA2B (0.43) | HPGDKDM4EALDH1A1GAAADRA2B | |
| SCHEMBL10786939 | 0.76 | LIPG (0.42) | LIPGMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726336-A | REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |