SCHEMBL2144342

SCHEMBL2144342

C=C(CC(=O)OC)C(=O)O[Si](C)(C)CCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.36
CA12 O43570 2/20 0.36
CA14 Q9ULX7 2/20 0.36
POLB P06746 1/20 0.36
POLA1 P09884 1/20 0.36
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
EPHX2 P34913 2/20 0.34
EPHX1 P07099 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.32
KDM5A P29375 2/20 0.31
RECQL P46063 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2144183 0.84 TSHR (0.38) TSHRMGAMGAASIMGAM2
SCHEMBL2144331 0.81 POLB (0.41) TSHRCA12CA14POLBPOLA1
SCHEMBL2144390 0.81 POLB (0.41) TSHRCA12CA14POLBPOLA1
SCHEMBL5838985 0.80 TSHR (0.48) TSHREPHX1ALDH1A1ACHE
SCHEMBL2144683 0.78 MGAM (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL8638694 0.76 ALOX15 (0.33)
SCHEMBL5973941 0.76 CA12 (0.34) TSHRCA12CA14CA2CA7
SCHEMBL21617936 0.74 EPHX1 (0.31) EPHX1
Butane SCHEMBL14335055 0.74 ALDH1A1 (0.42) TSHRCA12CA14POLBPOLA1
SCHEMBL7185234 0.74 TSHR (0.55) TSHREPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
EP-0802243-B1 Coating composition NOF CORP (JP) 2001-06-27 EP disclosed
US-5795374-A SILYL ACRYLATE POLYMERS NOF CORPORATION (JP) 1998-08-18 US disclosed
EP-0802243-A2 Coating composition NOF CORPORATION (JP) 1997-10-22 EP disclosed