Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 10/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6724348 | 0.73 | HDAC4 (0.54) | HDAC8HDAC4HDAC1HDAC6 | |
| SCHEMBL14952774 | 0.73 | HDAC4 (0.54) | HDAC8HDAC4HDAC1HDAC6 | |
| SCHEMBL10668988 | 0.73 | HDAC4 (0.54) | HDAC8HDAC4HDAC1HDAC6 | |
| SCHEMBL31105812 | 0.73 | HDAC4 (0.54) | HDAC8HDAC4HDAC1HDAC6 | |
| SCHEMBL4304535 | 0.70 | PSMB9 (0.41) | — | |
| SCHEMBL16258958 | 0.69 | OPRM1 (0.34) | HDAC4HDAC1 | |
| SCHEMBL12472216 | 0.67 | PSMB9 (0.37) | HDAC4HDAC1 | |
| SCHEMBL7953237 | 0.67 | PSMB9 (0.35) | — | |
| SCHEMBL12276304 | 0.67 | CTSD (0.62) | GHSRCTSD | |
| SCHEMBL14876390 | 0.66 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2850095-B1 | PEPTIDE AND PEPTIDOMIMETIC INHIBITORS | RA PHARMACEUTICALS INC (US) | 2019-10-09 | — | — | EP | disclosed |