Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25686202 | 0.87 | PARP14 (0.40) | PARP14ALOX5PRKDCEGFRIDO1 | |
| SCHEMBL19147809 | 0.86 | ALOX5 (0.46) | PARP14ALOX5PRKDCEGFRIDO1 | |
| SCHEMBL30192444 | 0.86 | PARP14 (0.43) | PARP14ALOX5PRKDCEGFRIDO1 | |
| SCHEMBL16802018 | 0.86 | PARP14 (0.43) | PARP14ALOX5PRKDCEGFRIDO1 | |
| SCHEMBL23558902 | 0.85 | PARP14 (0.37) | PARP14ALOX5PRKDCEGFR | |
| SCHEMBL21446536 | 0.83 | PTGIR (0.37) | PARP14ALOX5IDO1PTGIRPDK2 | |
| SCHEMBL17742402 | 0.83 | PTGIR (0.44) | PARP14IDO1PTGIRTDO2PDK2 | |
| SCHEMBL22680675 | 0.82 | RAB9A (0.34) | PARP14EGFRPDK2 | |
| SCHEMBL24969722 | 0.82 | PARP14 (0.35) | PARP14ALOX5EGFRIDO1PTGIR | |
| SCHEMBL24890009 | 0.81 | FADS1 (0.40) | PDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-05-20 | — | — | US | disclosed |
| WO-2019192954-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147375-A1 | MATERIALS FOR ELECTRONIC DEVICES | PNMT, EFNA1, TES | PARP14 1536/4885ALOX5 2210/4885PRKDC 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.