SCHEMBL21450432

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22301597	0.96	KDM4E (0.35)	KDM4EATML3MBTL1MAT2APRMT5
	SCHEMBL24948492	0.95	L3MBTL1 (0.46)	KDM4EATML3MBTL1ALDH1A1MAPT
	SCHEMBL21450464	0.95	ESR1 (0.36)	KDM4EATML3MBTL1CYP1A2ALDH1A1
	SCHEMBL24949157	0.95	L3MBTL1 (0.46)	KDM4EATML3MBTL1ALDH1A1MAPT
	SCHEMBL21452038	0.94	KDM4E (0.38)	KDM4EATML3MBTL1MAT2APRMT5
	SCHEMBL24032443	0.94	KDM4E (0.38)	KDM4EATML3MBTL1MAT2APRMT5
	SCHEMBL24032352	0.94	KDM4E (0.35)	KDM4EATML3MBTL1ALDH1A1MAPT
	SCHEMBL21452025	0.93	KDM4E (0.37)	KDM4EATML3MBTL1MAT2APRMT5
	SCHEMBL21450462	0.93	KDM4E (0.39)	KDM4EATML3MBTL1ALDH1A1MAPT
	SCHEMBL23283899	0.92	HTR1A (0.35)	KDM4EATML3MBTL1CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.