Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21461681 | 0.86 | KCNH2 (0.53) | KCNH2ALDH1A1BMP1MAPTRAB9A | |
| SCHEMBL21461679 | 0.82 | CA1 (0.49) | KCNH2ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL21461683 | 0.78 | CA12 (0.48) | KCNH2ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL13232030 | 0.74 | TSHR (0.44) | ALDH1A1GAACA12CA14SMN1; SMN2 | |
| SCHEMBL1350599 | 0.73 | MAPT (0.55) | KCNH2ALDH1A1MAPTRAB9A | |
| SCHEMBL1350027 | 0.73 | MAPT (0.57) | KCNH2ALDH1A1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL21461678 | 0.72 | KCNH2 (0.44) | KCNH2ALDH1A1BMP1CA12CA1 | |
| Hydrochloric Acid SCHEMBL21461677 | 0.72 | KCNH2 (0.44) | KCNH2ALDH1A1BMP1CA12CA1 | |
| SCHEMBL9149818 | 0.72 | TMEM97 (0.59) | KCNH2ALDH1A1MAPTRAB9ATMEM97 | |
| SCHEMBL16572325 | 0.71 | KCNH2 (0.48) | KCNH2ALDH1A1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10806140-B2 | Antimicrobial compound | PHYSICAL SCIENCES, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190313641-A1 | ANTIMICROBIAL COMPOUND | PHYSICAL SCIENCES, INC. | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190313641-A1 | ANTIMICROBIAL COMPOUND | NOD2, FPR1, NOD1 | KCNH2 2629/4885ALDH1A1 4048/4885ADRA1D 3357/4885 |
| US-10806140-B2 | Antimicrobial compound | FPR1, NOD1, NOS1 | KCNH2 2662/4885ALDH1A1 3563/4885ADRA1D 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.