Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21461678 | 0.98 | KCNH2 (0.44) | KCNH2ALDH1A1CA12CA1CA2 | |
| SCHEMBL21461683 | 0.80 | CA12 (0.48) | KCNH2ALDH1A1CA12CA1CA2 | |
| SCHEMBL21461679 | 0.76 | CA1 (0.49) | KCNH2ALDH1A1CA12CA1CA2 | |
| SCHEMBL11232034 | 0.74 | ALDH1A1 (0.60) | KCNH2ALDH1A1CA12CA1CA2 | |
| SCHEMBL11224190 | 0.73 | ALDH1A1 (0.61) | KCNH2ALDH1A1CA12CA1CA2 | |
| SCHEMBL21461680 | 0.72 | KCNH2 (0.47) | KCNH2ALDH1A1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL11440808 | 0.68 | PSMD14 (0.61) | KCNH2ALDH1A1MGLLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8987017 | 0.68 | PSMD14 (0.61) | KCNH2ALDH1A1MGLLMEN1KMT2A | |
| SCHEMBL8393893 | 0.67 | CNR1 (0.61) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8815105 | 0.67 | DNM1 (0.59) | KCNH2ALDH1A1MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10806140-B2 | Antimicrobial compound | PHYSICAL SCIENCES, INC. (US) | 2020-10-20 | — | — | US | disclosed |
| US-20190313641-A1 | ANTIMICROBIAL COMPOUND | PHYSICAL SCIENCES, INC. | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190313641-A1 | ANTIMICROBIAL COMPOUND | NOD2, FPR1, NOD1 | KCNH2 2629/4885ALDH1A1 4048/4885CA12 4064/4885 |
| US-10806140-B2 | Antimicrobial compound | FPR1, NOD1, NOS1 | KCNH2 2662/4885ALDH1A1 3563/4885CA12 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.