Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21465907 | 0.73 | HPGD (0.32) | — | |
| SCHEMBL15469243 | 0.72 | HSD17B10 (0.34) | KMT2AMEN1TDP1 | |
| SCHEMBL27969194 | 0.71 | SLC6A3 (0.32) | — | |
| SCHEMBL21465908 | 0.68 | OPRM1 (0.37) | — | |
| SCHEMBL20751484 | 0.68 | HDAC6 (0.39) | — | |
| SCHEMBL15417769 | 0.66 | SLC6A3 (0.33) | — | |
| SCHEMBL13624605 | 0.65 | SLC6A3 (0.40) | — | |
| SCHEMBL15469205 | 0.65 | CYP1A2 (0.37) | — | |
| SCHEMBL22375471 | 0.65 | FOLH1 (0.32) | — | |
| SCHEMBL16095853 | 0.64 | SMN1; SMN2 (0.43) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442789-B2 | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use | SUTRO BIOPHARMA, INC. (US) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442789-B2 | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use | DNPEP, SLC1A5, AADAT | KMT2A 1476/4885MEN1 1459/4885TDP1 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.