Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12377330 | 0.85 | NR1H4 (0.63) | MLYCDNPSR1NR1H4MAPTHDAC1 | |
| SCHEMBL2627052 | 0.82 | PLAU (0.58) | CYP17A1CYP3A4NR1H4MAPTHDAC1 | |
| SCHEMBL2903698 | 0.81 | NR1H4 (0.56) | CYP17A1CYP3A4NR1H4HDAC1ALDH1A1 | |
| SCHEMBL15317677 | 0.81 | NPSR1 (0.74) | NPSR1NR1H4MEN1KMT2A | |
| SCHEMBL10076788 | 0.80 | PLAU (0.60) | CYP17A1CYP3A4MLYCDNPSR1HPGDS | |
| SCHEMBL7477122 | 0.80 | NPC1 (0.56) | NPSR1HDAC1ALDH1A1MEN1NPC1 | |
| SCHEMBL3030047 | 0.80 | HPGDS (0.51) | CYP17A1CYP3A4MLYCDNPSR1HPGDS | |
| SCHEMBL26885174 | 0.80 | KDM4E (0.56) | CYP17A1CYP3A4MLYCDNPSR1NR1H4 | |
| SCHEMBL21467202 | 0.79 | CYP17A1 (0.40) | CYP17A1CYP3A4NR1H4MAPTHDAC1 | |
| SCHEMBL263634 | 0.79 | KIF11 (0.57) | CYP17A1CYP3A4NPSR1MAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158155-A1 | Cell Surface Receptor Binding Compounds and Conjugates | LYCIA THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-10441576-B2 | Substituted 1,2-dihydro-3H pyrrolo[1,2-c]imidazol-3 one antibacterials | IDORSIA PHARMACEUTICALS LTD. (CH) | 2019-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158155-A1 | Cell Surface Receptor Binding Compounds and Conjugates | M6PR, ASGR1, IGF2R | CYP17A1 4820/4885CYP3A4 3731/4885MLYCD 3774/4885 |
| US-10441576-B2 | Substituted 1,2-dihydro-3H pyrrolo[1,2-c]imidazol-3 one antibacterials | CTSH, MRPL21, CASP3 | CYP17A1 2118/4885CYP3A4 805/4885MLYCD 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.