Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968544 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TDP1HDAC3HDAC1HDAC2 | |
| SCHEMBL30616197 | 0.84 | ALDH1A1 (0.46) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR | |
| SCHEMBL10073706 | 0.83 | KMT2A (0.41) | CYP1A2CYP2C19ALDH1A1HDAC3HDAC1 | |
| SCHEMBL28330209 | 0.81 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR | |
| SCHEMBL4514786 | 0.81 | ALDH1A1 (0.43) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR | |
| SCHEMBL7867086 | 0.79 | TSHR (0.52) | ALDH1A1TSHRTDP1HDAC1POLB | |
| SCHEMBL25984799 | 0.79 | ALDH1A1 (0.42) | CYP2C19ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL2220361 | 0.78 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBHPGDHSD11B1 | |
| SCHEMBL4514669 | 0.77 | POLB (0.43) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR | |
| SCHEMBL14636054 | 0.76 | TDP1 (0.50) | CYP1A2CYP2D6CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753392-B2 | Method for synthesis of deuterated amide and deuterated sulfonamide | HINOVA PHARMACEUTICALS INC. (CN) | 2023-09-12 | — | — | US | disclosed |
| US-11753392-B2 | Method for synthesis of deuterated amide and deuterated sulfonamide | HINOVA PHARMACEUTICALS INC. (CN) | 2023-09-12 | — | — | US | disclosed |
| US-20210115009-A1 | METHOD FOR SYNTHESIS OF DEUTERATED AMIDE AND DEUTERATED SULFONAMIDE | HINOVA PHARMACEUTICALS INC. (CN) | 2021-04-22 | — | — | US | disclosed |
| EP-3778538-A1 | NOVEL METHOD FOR SYNTHESIZING DEUTERATED AMIDES AND DEUTERATED SULFONAMIDES | Hinova Pharmaceuticals Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |
| WO-2019196945-A1 | NOVEL METHOD FOR SYNTHESIZING DEUTERATED AMIDES AND DEUTERATED SULFONAMIDES | 成都海创药业有限公司 | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115009-A1 | METHOD FOR SYNTHESIS OF DEUTERATED AMIDE AND DEUTERATED SULFONAMIDE | SRM, NAAA, SNRPD2 | CYP1A2 2536/4885CYP2D6 1517/4885CYP2C19 4095/4885 |
| US-11753392-B2 | Method for synthesis of deuterated amide and deuterated sulfonamide | SRM, NAAA, SNRPD2 | CYP1A2 2536/4885CYP2D6 1517/4885CYP2C19 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.