SCHEMBL2968544

SCHEMBL2968544

Cc1ccc(C(=O)N(C)C(=O)OC(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
LMNA P02545 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HPGD P15428 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC2 Q92769 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
MAPT P10636 2/20 0.38
MMP13 P45452 1/20 0.38
ELANE P08246 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 2/20 0.37
PKM P14618 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10073706 0.85 KMT2A (0.41) ALDH1A1CES2CES1SMN1; SMN2HPGD
SCHEMBL21470599 0.84 CYP1A2 (0.46) ALDH1A1CES2CES1TDP1SMN1; SMN2
SCHEMBL24634985 0.81 CES2 (0.44) ALDH1A1LMNACES2CES1TDP1
SCHEMBL8334790 0.77 MMP13 (0.45) ALDH1A1LMNACES2CES1TDP1
SCHEMBL24634990 0.76 NPC1 (0.45) ALDH1A1LMNACES2CES1TDP1
SCHEMBL25571221 0.76 PPARG (0.41) ALDH1A1LMNACES2CES1TDP1
SCHEMBL14384381 0.75 PAX8 (0.50) ALDH1A1LMNASMN1; SMN2HSD17B1HSD17B2
SCHEMBL18082664 0.74 TDP1 (0.40) ALDH1A1TDP1SMN1; SMN2HDAC1HDAC3
SCHEMBL27383304 0.74 ALDH1A1 (0.54) ALDH1A1LMNACES2CES1TDP1
SCHEMBL318720 0.74 TDP1 (0.59) ALDH1A1LMNACES2CES1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed