Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.33 |
| ▸ | CDK9 | P50750 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23353691 | 0.91 | GHSR (0.35) | GHSRCCNT1CDK9KDM4E | |
| SCHEMBL23327019 | 0.90 | KDM4E (0.37) | KDM4E | |
| SCHEMBL23327021 | 0.90 | KDM4E (0.37) | KDM4E | |
| SCHEMBL21470775 | 0.84 | GHSR (0.37) | GHSRCCNT1CDK9 | |
| SCHEMBL21470777 | 0.84 | GHSR (0.37) | GHSRCCNT1CDK9 | |
| SCHEMBL21471032 | 0.81 | KIT (0.39) | CCNT1CDK9 | |
| SCHEMBL21471031 | 0.81 | KIT (0.39) | CCNT1CDK9 | |
| SCHEMBL21470702 | 0.78 | GHSR (0.33) | GHSRKDM4E | |
| SCHEMBL23326833 | 0.73 | KDM4E (0.36) | CCNT1CDK9KDM4EMET | |
| SCHEMBL21470766 | 0.73 | HTR6 (0.39) | GHSRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | GOSSAMER BIO SERVICES INC (US) | 2021-05-13 | — | — | US | disclosed |
| WO-2019200120-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | LYCERA CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139484-A1 | DIHYDROISOQUINOLINE-2(1H)-CARBOXAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ULK1, PHKG2, PHKG1 | GHSR 2448/4885CCNT1 1971/4885CDK9 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.