Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.44 |
| ▸ | TNKS | O95271 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425113 | 0.84 | SYK (0.56) | PTPRCPTPN1SYKTNKS2ALDH1A1 | |
| SCHEMBL23433177 | 0.81 | HPGD (0.50) | PTPRCPTPN1ALDH1A1MEN1KMT2A | |
| SCHEMBL23433235 | 0.76 | ALDH1A1 (0.43) | PTPRCPTPN1ALDH1A1MEN1KMT2A | |
| SCHEMBL13241158 | 0.76 | TNKS (0.53) | SYKTNKS2TNKSALDH1A1MEN1 | |
| SCHEMBL1044693 | 0.76 | NFE2L2 (0.51) | SYKTNKS2TNKSALDH1A1MAPT | |
| SCHEMBL11439546 | 0.75 | CA1 (0.67) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10093046 | 0.74 | ERN1 (0.49) | SYKTNKS2TNKSALDH1A1MAPT | |
| SCHEMBL21471599 | 0.74 | HDAC4 (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11499533 | 0.74 | SYK (0.53) | SYKALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7932563 | 0.74 | ERN1 (0.44) | SYKTNKS2TNKSALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163393-A1 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2021-06-03 | — | — | US | disclosed |
| WO-2019200314-A2 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163393-A1 | HINOKITIOL ANALOGUES, METHODS OF PREPARING AND PHARMACEUTICAL COMPOSITIONS THEREOF | CYP27A1, CYP27B1, HSD17B7 | PTPRC 3917/4885PTPN1 4666/4885SYK 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.