SCHEMBL21472974

SCHEMBL21472974

c1ccc2cc(-c3cccc4c5ccc6c7ccccc7c7cccc8c7c6c5n8c34)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.38
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP1A2 P05177 2/20 0.36
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
THRB P10828 1/20 0.36
S1PR4 O95977 2/20 0.35
S1PR5 Q9H228 2/20 0.35
PRKDC P78527 1/20 0.35
CNR2 P34972 1/20 0.35
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21472969 0.89 ALDH1A1 (0.31) ALDH1A1HPGDHSD17B10TSHRMAPK1
SCHEMBL21472965 0.88 GSTP1 (0.39) GSTP1HSD17B1HSD17B2HDAC4HDAC2
SCHEMBL21472971 0.85
SCHEMBL21472983 0.84 HSD17B1 (0.40) GSTP1HSD17B1HSD17B2ALDH1A1CYP1A2
SCHEMBL21472988 0.83 PRKDC (0.33) HPGDHSD17B10PRKDC
SCHEMBL21461880 0.83 MAPK14 (0.34) HSD17B10
SCHEMBL21472987 0.83 CDK4 (0.35) ALDH1A1CYP1A2HPGDHSD17B10THRB
SCHEMBL21473101 0.80 MEN1 (0.34) ALDH1A1HPGDHSD17B10TSHRMAPK1
SCHEMBL21473022 0.80 GSTP1 (0.37) GSTP1HSD17B1HSD17B2HDAC4HDAC2
SCHEMBL21718239 0.79 GSTP1 (0.43) GSTP1HSD17B1HSD17B2HDAC4HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315759-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OSBP, OSBP2, OSBPL3 GSTP1 1334/4885HSD17B1 1978/4885HSD17B2 2026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.