Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21473093 | 0.89 | TNF (0.42) | TNFDYRK1AIMPDH2CYP17A1CYP1A2 | |
| SCHEMBL21473094 | 0.89 | TNF (0.42) | TNFDYRK1AIMPDH2CYP17A1CYP1A2 | |
| SCHEMBL21461880 | 0.86 | MAPK14 (0.34) | CDK4CCND1 | |
| SCHEMBL21472987 | 0.83 | CDK4 (0.35) | CYP1A2CDK4CCND1 | |
| SCHEMBL21473101 | 0.81 | MEN1 (0.34) | CDK4CCND1 | |
| SCHEMBL21472988 | 0.79 | PRKDC (0.33) | CDK4CCND1 | |
| SCHEMBL21473035 | 0.78 | GABRP (0.32) | — | |
| SCHEMBL21473107 | 0.78 | PLG (0.33) | CDK4CCND1 | |
| SCHEMBL21473049 | 0.75 | CCNA2 (0.37) | TNFDYRK1ACDK4CCND1 | |
| SCHEMBL21472969 | 0.75 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315759-A1 | HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315759-A1 | HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES | OSBP, OSBP2, OSBPL3 | TNF 4748/4885DYRK1A 4816/4885IMPDH2 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.