Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799869 | 0.84 | ALDH1A1 (0.46) | CYP2C19KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1764576 | 0.82 | KMT2A (0.49) | CYP3A4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL21713063 | 0.80 | ALDH1A1 (0.35) | CYP3A4CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL12972246 | 0.79 | KMT2A (0.35) | CYP3A4KMT2AMEN1LMNACYP2C9 | |
| SCHEMBL13108203 | 0.79 | LMNA (0.35) | CYP3A4KMT2AMEN1LMNACYP2C9 | |
| SCHEMBL836758 | 0.78 | ALDH1A1 (0.33) | CYP3A4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL4698289 | 0.78 | ALDH1A1 (0.35) | CYP3A4CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL1346331 | 0.78 | MEN1 (0.31) | CYP3A4KMT2AMEN1LMNACYP2C9 | |
| SCHEMBL14948532 | 0.78 | MAPK1 (0.32) | CYP3A4KMT2AMEN1LMNACYP2C9 | |
| SCHEMBL14794931 | 0.77 | MEN1 (0.33) | CYP3A4KMT2AMEN1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091164-A1 | ORAL DOSAGE FORMS HAVING A HIGH LOADING OF A TRANEXAMIC ACID PRODRUG | XENOPORT, INC. (US) | 2011-07-28 | — | — | WO | disclosed |