Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698290 | 0.89 | MAPT (0.35) | ALDH1A1MEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL917125 | 0.87 | MEN1 (0.36) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4701760 | 0.86 | MAPT (0.42) | ALDH1A1BLMMEN1LMNACYP3A4 | |
| SCHEMBL2193456 | 0.85 | MEN1 (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4699686 | 0.85 | TDP1 (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL12972246 | 0.84 | KMT2A (0.35) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL4698309 | 0.81 | PRKCA (0.36) | MEN1LMNACYP3A4CYP2C9NFKB1 | |
| SCHEMBL1764576 | 0.81 | KMT2A (0.49) | ALDH1A1HPGDMEN1LMNACYP3A4 | |
| SCHEMBL4698375 | 0.79 | NAAA (0.43) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL4702471 | 0.79 | NAAA (0.47) | ALDH1A1CYP1A2HPGDCYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |