Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15643139 | 0.85 | KMT2A (0.36) | KMT2AATM | |
| SCHEMBL917125 | 0.85 | MEN1 (0.36) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL15892765 | 0.84 | KMT2A (0.35) | KMT2AATM | |
| SCHEMBL4698289 | 0.84 | ALDH1A1 (0.35) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4699686 | 0.83 | TDP1 (0.35) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL2193456 | 0.83 | MEN1 (0.35) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL1764576 | 0.82 | KMT2A (0.49) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL4698290 | 0.81 | MAPT (0.35) | KMT2AMEN1LMNACYP3A4CYP2C9 | |
| SCHEMBL12741112 | 0.81 | ELANE (0.37) | KMT2ALMNAATM | |
| SCHEMBL917156 | 0.80 | GLA (0.34) | KMT2AMEN1LMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815793-B2 | Polymeric compositions and related methods of use | NORTHWESTERN UNIVERSITY (US) | 2014-08-26 | — | — | US | disclosed |
| US-7858679-B2 | Polymeric compositions and related methods of use | NORTHWESTERN UNIVERSITY (US) | 2010-12-28 | — | — | US | disclosed |
| US-7618937-B2 | Peptidomimetic polymers for antifouling surfaces | NORTHWESTERN UNIVERSITY (US) | 2009-11-17 | — | — | US | disclosed |