SCHEMBL21477512

SCHEMBL21477512

O=c1oc2c(c3ccccc13)CCCCCCCC2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
CASP1 P29466 1/20 0.41
ELANE P08246 3/20 0.41
CYP1A2 P05177 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
CYP2C19 P33261 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
CTSG P08311 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4712249 0.98 PARP1 (0.46) PARP1HSD17B10TSHRMAPK1HTT
SCHEMBL30023090 0.78 ALDH1A1 (0.47) HSD17B10MAPK1ALDH1A1KDM4EHPGD
SCHEMBL23537551 0.78 ALDH1A1 (0.47) HSD17B10MAPK1ALDH1A1KDM4EHPGD
SCHEMBL23537530 0.74 ALDH1A1 (0.47) HSD17B10HTTALDH1A1KDM4EHPGD
SCHEMBL31217612 0.74 MAOA (0.53) HSD17B10MAPK1ALDH1A1KDM4EHPGD
SCHEMBL313890 0.74 CYP3A4 (0.56) HSD17B10TSHRALDH1A1KDM4EHPGD
SCHEMBL3628571 0.72 MAOA (0.55) HSD17B10MAPK1ALDH1A1KDM4EHPGD
SCHEMBL29576889 0.72 MAOA (0.55) HSD17B10MAPK1ALDH1A1KDM4EHPGD
SCHEMBL28360801 0.72 CYP1A2 (0.61) HSD17B10TSHRALDH1A1KDM4EHPGD
SCHEMBL24891350 0.71 ELANE (0.61) HSD17B10MAPK1ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935291-B1 IRIDIUM COMPLEXES USED IN OLIGOMERS, POLYMERS OR DENDRIMERS IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-10-16 EP disclosed