SCHEMBL21485070

SCHEMBL21485070

CN1C(O)C=CN1c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.33
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
ABCB11 O95342 1/20 0.31
LMNA P02545 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC18A3 Q16572 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
LOX P28300 1/20 0.30
LOXL3 P58215 1/20 0.30
LOXL4 Q96JB6 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28858304 0.79 LOX (0.35) MAPK1GSK3AGSK3BSMN1; SMN2LOX
SCHEMBL22005629 0.64 SLC6A4 (0.33) ABCB11LMNAPTGS1SLC18A3SMN1; SMN2
SCHEMBL28318975 0.64 MAOA (0.31) LOXLOXL3LOXL4LOXL2
SCHEMBL28192531 0.64 MAOA (0.31) LOXLOXL3LOXL4LOXL2
SCHEMBL20267546 0.63
SCHEMBL10067910 0.60 MGLL (0.43) GSK3AGSK3BABCB11LMNAPTGS1
SCHEMBL4989924 0.60 SIGMAR1 (0.40) MAPK1GSK3AGSK3BLMNAALDH1A1
SCHEMBL12589187 0.60 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1
SCHEMBL19291106 0.60 MGLL (0.43) GSK3AGSK3BABCB11LMNAPTGS1
SCHEMBL21485066 0.60 GSK3A (0.35) GSK3AGSK3BLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555098-A1 MESOIONIC IMIDAZOPYRIDINES FOR USE AS INSECTICIDES Bayer Aktiengesellschaft (DE) 2019-10-23 EP disclosed