Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD4 | Q15561 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19602284 | 0.79 | ACHE (0.52) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL17423587 | 0.78 | MAPT (0.45) | MAPTALDH1A1POLBLPAR1LPAR5 | |
| SCHEMBL5539624 | 0.78 | LPAR1 (0.40) | MAPTPOLBLPAR1LPAR5SLC6A4 | |
| SCHEMBL1129355 | 0.78 | MAPT (0.45) | MAPTALDH1A1POLBLPAR1LPAR5 | |
| SCHEMBL15515736 | 0.78 | ALDH1A1 (0.54) | TEAD4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13861391 | 0.78 | LPAR1 (0.40) | MAPTPOLBLPAR1LPAR5SLC6A4 | |
| SCHEMBL3874015 | 0.78 | TEAD4 (0.59) | TEAD4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18181866 | 0.78 | SLC6A4 (0.45) | TEAD4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8035743 | 0.77 | PARP10 (0.56) | TEAD4MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16415975 | 0.75 | SLC6A2 (0.45) | ACHELPAR1LPAR5SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147428-A1 | METHOD FOR PREPARING PYRROLOAMINOPYRIDAZINONE COMPOUND AND INTERMEDIATES THEREOF | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2021-05-20 | — | — | US | disclosed |
| WO-2019196915-A1 | METHOD FOR PREPARING PYRROLOAMINOPYRIDAZINONE COMPOUND AND INTERMEDIATES THEREOF | 江苏恒瑞医药股份有限公司 | 2019-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147428-A1 | METHOD FOR PREPARING PYRROLOAMINOPYRIDAZINONE COMPOUND AND INTERMEDIATES THEREOF | DHPS, PPOX, PNPO | TEAD4 2859/4885MEN1 2295/4885KMT2A 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.