SCHEMBL2149602

SCHEMBL2149602

CC(=O)OCC1C(C(=O)O)C1(C)C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
HSD17B10 Q99714 1/20 0.34
PDK1 Q15118 1/20 0.30
NLRP3 Q96P20 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3357854 1.00 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10PDK1NLRP3
SCHEMBL11008632 1.00 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10PDK1NLRP3
SCHEMBL10507865 1.00 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10PDK1NLRP3
SCHEMBL10507877 1.00 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10PDK1NLRP3
SCHEMBL27752062 0.83 TSHR (0.35) LMNATSHR
SCHEMBL27752051 0.81 HPGD (0.30) TSHR
SCHEMBL2149721 0.81 NAAA (0.37) ALDH1A1LMNACYP1A2CYP2C19
SCHEMBL1150190 0.81 LMNA (0.34) ALDH1A1LMNAHSD17B10
SCHEMBL2232034 0.81 LMNA (0.31) LMNA
SCHEMBL1685675 0.79 PRKCA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116135835-B Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2025-02-25 CN claimed
CN-117263791-A Method for preparing 3, 3-dimethyl-1, 2-cyclopropane dicarboxylic acid 中国科学院大连化学物理研究所 2023-12-22 CN claimed
CN-116135835-A Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2023-05-19 CN claimed
EP-0149289-B1 PROCESS FOR THE MANUFACTURE OF AN OPTICALLY ACTIVE LACTONE OF A CYCLOPROPANE-CARBOXYLIC ACID IEL Limited (IN) 1989-01-04 EP claimed
US-4568758-A TWO-STAGE OXIDATION OF CAR-3-EN-5-ONE AND HYDROLYSIS OF INTERMEDIATE INDIAN EXPLOSIVES LIMITED (IN) 1986-02-04 US claimed
EP-0149289-A1 Process for the manufacture of an optically active lactone of a cyclopropane-carboxylic acid IEL Limited (IN) 1985-07-24 EP claimed
CN-116135835-B Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2025-02-25 CN disclosed
CN-117263791-A Method for preparing 3, 3-dimethyl-1, 2-cyclopropane dicarboxylic acid 中国科学院大连化学物理研究所 2023-12-22 CN disclosed
CN-116135835-A Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2023-05-19 CN disclosed
EP-2341042-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2019-03-20 EP disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
US-8680328-B2 Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-25 US disclosed
EP-0051791-A1 2,2-Dimethylcyclobutanones and process for their preparation BAYER AG (DE) 1982-05-19 EP disclosed
US-4258207-A Cyclopropanecarboxylate pesticides preparation SHELL OIL COMPANY (US) 1981-03-24 US disclosed
US-4241081-A Cyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-12-23 US disclosed
US-4223155-A 3-(Hydrocarbylthiomethyl)-2,2-dimethyl-cyclopropanecarboxylate pesticides and their preparation SHELL OIL COMPANY (US) 1980-09-16 US disclosed
US-4219658-A PESTICIDES SHELL OIL COMPANY (US) 1980-08-26 US disclosed
US-4219562-A 3-(Hydrocarbylthiomethyl)-2,2-dimethylcyclopropanecarboxylate pesticides SHELL OIL COMPANY (US) 1980-08-26 US disclosed
US-4209642-A Cyclopropylmethanol pesticide SHELL OIL COMPANY (US) 1980-06-24 US disclosed