Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14718746 | 0.82 | CYP11B1 (0.50) | CYP11B1ALDH1A1HSD17B10HIF1ATSHR | |
| SCHEMBL29362973 | 0.82 | CYP11B1 (0.50) | CYP11B1ALDH1A1HSD17B10HIF1ATSHR | |
| SCHEMBL2128249 | 0.81 | MEN1 (0.49) | ALDH1A1HSD17B10HPGDMAPK1NISCH | |
| SCHEMBL29406150 | 0.81 | MEN1 (0.49) | ALDH1A1HSD17B10HPGDMAPK1NISCH | |
| SCHEMBL14725247 | 0.81 | CYP11B1 (0.49) | CYP11B1ALDH1A1HSD17B10HIF1ATSHR | |
| SCHEMBL14725245 | 0.81 | CYP11B1 (0.49) | CYP11B1ALDH1A1TSHRHPGDL3MBTL1 | |
| SCHEMBL29751148 | 0.80 | CYP11B1 (0.35) | CYP11B1HPGDL3MBTL1NISCHHPRT1 | |
| SCHEMBL27926692 | 0.79 | MEN1 (0.47) | ALDH1A1HSD17B10HPGDMAPK1NISCH | |
| SCHEMBL14725233 | 0.79 | MEN1 (0.47) | ALDH1A1HSD17B10HPGDMAPK1NISCH | |
| SCHEMBL14725274 | 0.78 | CYP11B1 (0.46) | CYP11B1ALDH1A1HSD17B10HIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10454043-B2 | Heterocyclic compound and organic light-emitting element using same | HEESUNG MATERIAL LTD. (KR) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10454043-B2 | Heterocyclic compound and organic light-emitting element using same | CRY1, CRY2, PER2 | CYP11B1 1115/4885ALDH1A1 953/4885HSD17B10 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.