Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728335 | 0.76 | GABRA1 (0.33) | — | |
| SCHEMBL28667869 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL15007 | 0.73 | KDM4E (0.61) | KDM4EL3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL16703905 | 0.72 | — | — | |
| SCHEMBL830410 | 0.69 | KDM4E (0.38) | KDM4EL3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL422266 | 0.69 | — | — | |
| SCHEMBL28464701 | 0.69 | PDXK (0.39) | KDM4EL3MBTL1PDXK | |
| SCHEMBL11456047 | 0.69 | PDXK (0.38) | KDM4EL3MBTL1PDXKNOS3NOS1 | |
| SCHEMBL9171315 | 0.69 | PDXK (0.34) | KDM4EL3MBTL1PDXK | |
| SCHEMBL19792099 | 0.67 | NOS3 (0.36) | KDM4EL3MBTL1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209651-B9 | CARBAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2020-05-20 | — | — | EP | disclosed |
| EP-3209651-B1 | CARBAZOLE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2019-10-23 | — | — | EP | disclosed |