SCHEMBL21510253

SCHEMBL21510253

CC1(C)c2ccccc2N(c2ccc3c(c2)C(C)(C)c2ccc(-c4ccc(P(=O)(c5ccccc5)c5ccccc5)cc4)cc2C3(C)C)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.32
▸ ITGB2 P05107 1/20 0.32
▸ ICAM1 P05362 1/20 0.32
▸ ITGAL P20701 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21510466 0.90 ESR1 (0.30) —
SCHEMBL21510271 0.90 LMNA (0.30) LMNA
SCHEMBL21510255 0.89 HDAC6 (0.38) LMNAMEN1MAPTKMT2A
SCHEMBL13832913 0.88 PGR (0.36) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL13231589 0.86 LMNA (0.39) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL13833004 0.84 PGR (0.35) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL13833002 0.83 PGR (0.33) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL13833016 0.82 ALDH1A1 (0.42) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL13832919 0.82 PGR (0.34) LMNAITGB2ICAM1ITGALMEN1
SCHEMBL20230677 0.82 HTR6 (0.35) LMNAITGB2ICAM1ITGALMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190322623-A1 COMPOUND, DISPLAY PANEL, AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2019-10-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190322623-A1 COMPOUND, DISPLAY PANEL, AND DISPLAY APPARATUS DRD2, GRIN2D, DRD1 LMNA 1991/4885ITGB2 85/4885ICAM1 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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