SCHEMBL21519838

SCHEMBL21519838

NC(=O)C(CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 7/20 0.48
▸ CTSB P07858 2/20 0.47
▸ DPP4 P27487 3/20 0.45
▸ FAP Q12884 1/20 0.45
▸ DPP8 Q6V1X1 1/20 0.45
▸ DPP9 Q86TI2 1/20 0.45
▸ DPP7 Q9UHL4 1/20 0.45
▸ PLG P00747 2/20 0.40
▸ PLAT P00750 2/20 0.40
▸ OPRM1 P35372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2184762 1.00 CAPN1 (0.48) CAPN1CTSBDPP4FAPDPP8
SCHEMBL2194423 1.00 CAPN1 (0.48) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29616517 0.98 CAPN1 (0.51) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30800860 0.90 DPP4 (0.44) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29397117 0.89 DPP4 (0.46) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30800861 0.89 DPP4 (0.43) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29397226 0.87 DPP4 (0.44) CAPN1CTSBDPP4FAPDPP8
SCHEMBL15481300 0.87 DPP4 (0.42) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30800866 0.84 DPP4 (0.40) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29765255 0.84 CAPN1 (0.47) CAPN1CTSBDPP4FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 — — US disclosed
US-20190328887-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIVERSITÉ DE STRASBOURG (FR) 2019-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190328887-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GRPR CAPN1 4671/4885CTSB 1685/4885DPP4 342/4885
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS GPR119, GLP1R, GIPR CAPN1 4622/4885CTSB 1514/4885DPP4 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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