SCHEMBL30800866

SCHEMBL30800866

NC(=O)[C@H](CSS(=O)(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 6/20 0.40
▸ FAP Q12884 1/20 0.40
▸ DPP8 Q6V1X1 1/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ DPP7 Q9UHL4 1/20 0.40
▸ PLG P00747 2/20 0.37
▸ PLAT P00750 2/20 0.37
▸ CAPN1 P07384 4/20 0.36
▸ CTSB P07858 1/20 0.36
▸ OPRM1 P35372 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2194423 0.84 CAPN1 (0.48) DPP4FAPDPP8DPP9DPP7
SCHEMBL2184762 0.84 CAPN1 (0.48) DPP4FAPDPP8DPP9DPP7
SCHEMBL21519838 0.84 CAPN1 (0.48) DPP4FAPDPP8DPP9DPP7
SCHEMBL30800860 0.83 DPP4 (0.44) DPP4FAPDPP8DPP9DPP7
SCHEMBL30800861 0.82 DPP4 (0.43) DPP4FAPDPP8DPP9DPP7
SCHEMBL29616517 0.82 CAPN1 (0.51) DPP4FAPDPP8DPP9DPP7
SCHEMBL15481300 0.81 DPP4 (0.42) DPP4FAPDPP8DPP9DPP7
SCHEMBL29397117 0.79 DPP4 (0.46) DPP4FAPDPP8DPP9DPP7
SCHEMBL30852867 0.77 CAPN1 (0.41) DPP4FAPDPP8DPP9DPP7
SCHEMBL29397226 0.77 DPP4 (0.44) DPP4FAPDPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3688007-B1 BIOCONJUGATION OF POLYPEPTIDES UNIV YORK (GB) 2024-07-31 — — EP disclosed
US-11897917-B2 Bioconjugation of polypeptides THE UNIVERSITY OF YORK (GB) 2024-02-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897917-B2 Bioconjugation of polypeptides PTMS, EPCAM, IAPP DPP4 1509/4885FAP 98/4885DPP8 1170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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