SCHEMBL29616517

SCHEMBL29616517

NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 8/20 0.51
▸ CTSB P07858 3/20 0.50
▸ DPP4 P27487 3/20 0.43
▸ FAP Q12884 1/20 0.43
▸ DPP8 Q6V1X1 1/20 0.43
▸ DPP9 Q86TI2 1/20 0.43
▸ DPP7 Q9UHL4 1/20 0.43
▸ PLG P00747 2/20 0.39
▸ PLAT P00750 2/20 0.39
▸ OPRM1 P35372 1/20 0.38
▸ VHL P40337 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2194423 0.98 CAPN1 (0.48) CAPN1CTSBDPP4FAPDPP8
SCHEMBL2184762 0.98 CAPN1 (0.48) CAPN1CTSBDPP4FAPDPP8
SCHEMBL21519838 0.98 CAPN1 (0.48) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29397226 0.90 DPP4 (0.44) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30800860 0.88 DPP4 (0.44) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29397117 0.87 DPP4 (0.46) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30800861 0.87 DPP4 (0.43) CAPN1CTSBDPP4FAPDPP8
SCHEMBL29765255 0.86 CAPN1 (0.47) CAPN1CTSBDPP4FAPDPP8
SCHEMBL30852867 0.86 CAPN1 (0.41) CAPN1CTSBDPP4FAPDPP8
SCHEMBL15481300 0.85 DPP4 (0.42) CAPN1CTSBDPP4FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis SANOFI (FR) 2022-06-07 — — US claimed
US-20260116928-A1 COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY THORNHILL THERAPEUTICS INC (US) 2026-04-30 — — US disclosed
US-20260055154-A1 LONG-ACTING DUAL-AGONIST COMPOUND CHENGDU AODA BIOTECHNOLOGY CO LTD (CN) 2026-02-26 — — US disclosed
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications SHENZHEN TURIER BIOTECH CO., LTD (CN) 2023-06-15 — — US disclosed
US-11504433-B2 Cholix-derived carriers for oral delivery of heterologous payload APPLIED MOLECULAR TRANSPORT INC. (US) 2022-11-22 — — US disclosed
US-20220275029-A1 COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY THORNHILL THERAPEUTICS, INC. 2022-09-01 — — US disclosed
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis SANOFI (FR) 2022-06-07 — — US disclosed
US-11324833-B2 Cholix-derived carriers for oral delivery of heterologous payload APPLIED MOLECULAR TRANSPORT INC. (US) 2022-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications IAPP, PNLIP, DPP4 CAPN1 2127/4885CTSB 110/4885DPP4 3/4885
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis GLP1R, GCGR, GIPR CAPN1 4524/4885CTSB 1945/4885DPP4 26/4885
US-20260055154-A1 LONG-ACTING DUAL-AGONIST COMPOUND GIPR, GLP1R, GCG CAPN1 2622/4885CTSB 1792/4885DPP4 81/4885
US-20260116928-A1 COMPOSITIONS AND PARTICLES FOR PAYLOAD DELIVERY SLC47A2, SLC47A1, SLC39A14 CAPN1 769/4885CTSB 356/4885DPP4 2306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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