Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152243 | 0.85 | KMT2A (0.45) | CA1CA2CA9ADRA2AADRA2B | |
| SCHEMBL10137032 | 0.79 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL22897010 | 0.78 | SLC6A4 (0.40) | — | |
| SCHEMBL477696 | 0.78 | LMNA (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL477543 | 0.78 | LMNA (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL477685 | 0.78 | LMNA (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL30986717 | 0.78 | LMNA (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Acetic Acid SCHEMBL28094249 | 0.78 | ALDH1A1 (0.53) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL710483 | 0.77 | AKR1B1 (0.42) | PTGS2 | |
| SCHEMBL14033381 | 0.77 | CA1 (0.61) | CA1CA2CA9PTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692101-B1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-07-06 | — | — | EP | claimed |
| US-7250446-B2 | Mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-07-31 | — | — | US | claimed |
| EP-1692101-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2006-08-23 | — | — | EP | claimed |
| US-20040229869-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-11-18 | — | — | US | claimed |
| WO-2004087644-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | claimed |
| EP-1692101-B1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2011-07-06 | — | — | EP | disclosed |
| US-7582653-B2 | Mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-01 | — | — | US | disclosed |
| US-20070244161-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-10-18 | — | — | US | disclosed |
| US-7250446-B2 | Mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-07-31 | — | — | US | disclosed |
| EP-1692101-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2006-08-23 | — | — | EP | disclosed |
| US-20040229869-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-11-18 | — | — | US | disclosed |
| WO-2004087644-A1 | MERCAPTO-PHENYL-NAPHTHYL-METHANE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244161-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | BRCA1, PGR, APC | CA1 1528/4885CA2 3811/4885CA9 2225/4885 |
| US-20040229869-A1 | Novel mercaptophenyl naphthyl methane compounds and synthesis thereof | BRCA1, PGR, APC | CA1 1528/4885CA2 3811/4885CA9 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.